Relevant Publications from the London Brain BioBank
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Mackenzie IR, Nicholson AM, Sarkar M, Messing J, Purice MD, Pottier C, Annu K, Baker M, Perkerson RB, Kurti A, Matchett BJ, Mittag T, Temirov J, Hsiung GR, Krieger C, Murray ME, Kato M, Fryer JD, Petrucelli L, Zinman L, Weintraub S, Mesulam M, Keith J, Zivkovic SA, Hirsch-Reinshagen V, Roos RP, Züchner S, Graff-Radford NR, Petersen RC, Caselli RJ, Wszolek ZK, Finger E, Lippa C, Lacomis D, Stewart H, Dickson DW, Kim HJ, Rogaeva E, Bigio E, Boylan KB, Taylor JP, Rademakers R.;TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics. Neuron. 2017 Aug 16;95(4):808-816.e9. doi: 10.1016/j.neuron.2017.07.025. PMID: 28817800.
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Taylor RG, Alyamany B, Pandey S, Kertesz A, Ang LC, Finger E. Looking Glass Syndromes: Two Sides of the Same Gene. Can J Neurol Sci. 2019 Jan;46(1):115-120. doi: 10.1017/cjn.2018.354. PMID: 30688199.
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Diodati D, Cyn-Ang L, Kertesz A, Finger E. Pathologic evaluation of the supraoptic and paraventricular nuclei in dementia. Can J Neurol Sci. 2012 Mar;39(2):213-9. doi: 10.1017/s0317167100013251. PMID: 22343156.
Roseborough, A, Langdon, KD, Hammond, R, Cipriano, LE, Pasternak, SH, Khan, AR, Whitehead, S, (2020) Post-mortem 7 Tesla MRI detection of white matter hyperintensities: A multidisciplinary voxel-wise comparison of imaging and histological correlates. NeuroImage, 2020;27:102340. doi: 10.1016/j.nicl.2020.102340. Epub 2020 Jul 6. PMID: 32679554
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Valeriy G. Ostapchenko, Jonathan Snir, Mojmir Suchy, Jue Fan, M. Rebecca Cobb, Michael Kovacs, Vania F. Prado, Robert Hudson, Stephen Pasternak, Marco Antonio Maximo Prado, Robert Bartha, (2019) Detection of Active Caspase 3 in mouse models of Alzheimer’s disease and Stroke with a Novel Dual Positron Emission Tomography and Fluorescent Contrast Agent Contrast Media and Molecular Imaging, Contrast Media Mol Imaging. 2019 Jan 14; DOI: 10.1155/2019/6403274. PMID: 30755766.
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JL Wells, Pasternak, SH. (2019) Case Report of a 63-Year-Old Patient With Alzheimer Disease and a Novel Presenilin 2 Mutation. Alzheimer Dis Assoc Discord, Apr-Jun;33(2):166-169. doi: 10.1097/WAD.0000000000000269. PMID: 30119059.
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Coakeley S, Ang LC, Jansen GH, Cho SS, Lang AE, Houle S, Kalia LV, Strafella
AP. [(18) F]AV-1451 binding and postmortem pathology of CBD. Mov Disord. 2018 Aug;33(8):1360-1361. doi: 10.1002/mds.27356. PMID: 30136331.
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Tong J, Rathitharan G, Meyer JH, Furukawa Y, Ang LC, Boileau I, Guttman M,
Hornykiewicz O, Kish SJ. Brain monoamine oxidase B and A in human parkinsonian dopamine deficiency disorders. Brain. 2017 Sep 1;140(9):2460-2474. doi: 10.1093/brain/awx172. PMID: 29050386.
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Kurdi M, Chin E, Ang LC. Granulovacuolar Degeneration in Hippocampus of Neurodegenerative Diseases: Quantitative Study. J Neurodegener Dis., 2016;2016:6163186. PMID: 27843674.
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Tong J, Ang LC, Williams B, Furukawa Y, Fitzmaurice P, Guttman M, Boileau I, Hornykiewicz O, Kish SJ. Low levels of astroglial markers in Parkinson's disease: relationship to α-synuclein accumulation. Neurobiol Dis. 2015 Oct;82:243-253. doi: 10.1016/j.nbd.2015.06.010. PMID: 26102022.
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Alturkustani M, Keith J, Hazrati LN, Rademakers R, Ang LC. Pathologic staging of white matter lesions in adult-onset leukoencephalopathy/leukodystrophy with axonal spheroids. J Neuropathol Exp Neurol. 2015 Mar;74(3):233-40. doi: 10.1097/NEN.0000000000000168. PMID: 25668567.
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Al Sufiani F, Ang LC. Neuropathology of temporal lobe epilepsy. Epilepsy Res Treat. 2012;2012:624519. doi: 10.1097/00005072-199309000-00001. PMID: 8360697.
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Keller BA, Volkening K, Droppelmann CA, Ang LC, Rademakers R, Strong MJ. Co-aggregation of RNA binding proteins in ALS spinal motor neurons: evidence of acommon pathogenic mechanism. Acta Neuropathol. 2012 Nov;124(5):733-47. doi: 10.1007/s00401-012-1035-z. PMID: 22941224.
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Mackenzie IR, Ansorge O, Strong M, Bilbao J, Zinman L, Ang LC, Baker M, Stewart H, Eisen A, Rademakers R, Neumann M. Pathological heterogeneity in myotrophic lateral sclerosis with FUS mutations: two distinct patterns
correlating with disease severity and mutation. Acta Neuropathol. 2011 Jul;122(1):87-98. doi: 10.1007/s00401-011-0838-7. PMID: 21604077.
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Keith-Rokosh J, Ang LC. Progressive supranuclear palsy: a review of co-existing neurodegeneration. Can J Neurol Sci. 2008 Nov;35(5):602-8. doi: 10.1017/s0317167100009392. PMID: 19235444.
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Gupta, N., Ang, L.C., De Tilly, L.N., Bidaisee, L. and Yücel, Y.H., 2006. Human glaucoma and neural degeneration in intracranial optic nerve, lateral geniculate nucleus, and visual cortex. British Journal of Ophthalmology, 90 (6), pp.674-678. doi: 10.1136/bjo.2005.086769. PMID: 16464969.
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Ang LC, Zhang Y, Cao L, Yang BL, Young B, Kiani C, Lee V, Allan K, Yang BB. Versican enhances locomotion of astrocytoma cells and reduces cell adhesion through its G1 domain. J Neuropathol Exp Neurol. 1999 Jun;58(6):597-605. doi: 10.1097/00005072-199906000-00004. PMID: 10374750.
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Subbarao KV, Richardson JS, Ang LC. Autopsy samples of Alzheimer's cortex show increased peroxidation in vitro.
J Neurochem. 1990 Jul;55(1):342-5. doi: 10.1111/j.1471-4159.1990.tb08858.x. PMID: 2355227.
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Murad Alturkustani, Qi Zhang, Basma AlYamany, Lee-Cyn Ang. Loss of Ramified Microglia Precedes Axonal Spheroids Formation in Adult-onset Leukoencephalopathy with Axonal Spheroids. Free Neuropathology, 2020 Oct 1; 1 (26): 1-12, Coauthor, DOI: https://doi.org/10.17879/freeneuropathology-2020-2971.
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Zheng H, Baranova K, Song J, Yan L, Biswas S, Chakrabarti S, Zhang Q. Overexpression of Long Noncoding RNA HOTAIR Is a Unique Epigenetic Characteristic of Myxopapillary Ependymoma. J Neuropathol Exp Neurol, 2020 Nov 1; 79 (11): 1193-1202, Senior Responsible Author, DOI: 10.1093/jnen/nlaa103. PMID: 32940681.
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Wang J, Qin J, Wang P, Sun Y, Zhang Q. Molecular Mechanisms of Glial Cells Related Signaling Pathways Involved in the Neuroinflammatory Response of Depression. Mediators Inflamm, 2020 Oct 1; 2020 (na): 3497920, Senior Responsible Author, DOI: 10.1155/2020/3497920. PMID: 33100903.
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Alturkustani M, Bahakeem B, Zhang Q, Ang LC. Different pathological processes for acute white matter lesions in multiple sclerosis. Malays J Pathol, 2020 Aug 1; 42 (2): 187-194. PMID: 32860370.
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Naeem AH, Kubica M, Namavarian A, Pandey S, Zhang Q. A 63-Year-Old Male with Cauda Equina Syndrome. Brain Pathol, 2020 Mar 1; 30 (2): 409-410, Senior Responsible Author, DOI: 10.1111/bpa.12816. PMID: 32100429.
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Yan L, Chakrabarti S, Zhang Q. Subretinal sclerosing hemangioma: A rare case report. Canadian Journal of Pathology, 2020 Feb 1; 2019-11 (4): 25-29, Senior Responsible Author
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Choi V, Kim DD, Fridman S, Zhang Q, Boulton M, Sposato LA. Pearls & Oy-sters: Giant descending aortic arch donut sign: Retrograde embolism as a cause of acute ischemic stroke. Neurology, 2019 Feb 26; 92 (9): 443-445, co-author, DOI: 10.1212/WNL.0000000000007011. PMID: 30804057.
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Zhang Q, Shibani A, Sadikovic B, Howlett CJ, Ang LC. An aggressive multifocal primary CNS histiocytosis with PTPN11 (Shp2) mutation. Neuropathol Appl Neurobiol, 2018 Feb 1; 44 (2): 240-243, Principal Author, DOI: 10.1111/nan.12404. PMID: 28403515.
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Zhang Q, Pocrnich C, Kurian A, Hahn AF, Howlett C, Shepherd J, Rizkalla K. Amyloid deposition in extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue: A clinicopathologic study of 5 cases. Pathol Res Pract, 2016 Mar 1; 212 (3): 185-9, Principal Author. DOI: 10.1016/j.prp.2015.08.007. PMID: 26847730.
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